Edgar M. Carvalho
Possui graduação em Medicina pela Universidade Federal da Bahia (1973), especialização em Reumatologia e Imunologia pela University of Virginia (1979), Mestrado em Medicina e Saúde pela Universidade Federal da Bahia (1977), Doutorado em Medicina e Saúde pela Universidade Federal da Bahia (1986) e Pós-doutorado em Imunologia na Cornell University (1990-1991). Atualmente é Professor Titular de Clínica Médica da Universidade Federal da Bahia, Professor Titular de Imunologia da Escola Bahiana de Medicina e Saúde Pública e Chefe do Serviço de Imunologia do Hospital Universitário Professor Edgard Santos. É também Professor Adjunto da Cornell University Medical College e Professor Adjunto da University of Iowa. É editor associado do Plos Neglected Tropical Diseases, da Case Reports in Medicine, da Revista Brasileira de Medicina Tropical e é membro do corpo editorial do Journal of Infectious Diseases. Tem formação em Clínica Médica com ênfase em imunologia clínica, doenças tropicais, reumatologia e alergia, e tem como principais áreas de atuação em pesquisa a Imunopatogênese das leishmanioses, imunopatologia e manifestações clínicas associadas à infecção pelo HTLV-1, Influência das helmintíases na resposta imune das doenças inflamatórias crônicas e doenças auto-imunes e Imunoterapia nas doenças infecciosas. Foi bolsista do Howard Hugges, é Coordenador do Instituto Nacional de Ciência e Tecnologia em Medicina Tropical e já coordenou vários Programas de Núcleo de Excelência.Pesquisador 1A do CNPq.
- Alexsandro Souza do Lago - Doutorado 2017
- Alexsandro Souza do Lago - Mestrado 2015
- Anselmo de Santana Souza – Doutorado 2009
- Camila Farias Amorim - Doutorado 2014
- Camila Farias Amorim – Mestrado 2012
- Carvel Suprien
- Cassius José Vitor de Oliveira - Doutorado 2016.2
- Cassius José Vitor de Oliveira - Mestrado 2014
- Clara Mônica Figueredo de Lima – Doutorado 2013
- Clara Monica Figueredo de Lima – Mestrado 2010
- Cleriston Farias Queiroz - Doutorado 2015.2
- Cleriston Queiroz – Mestrado 2013
- Davi Tanajura Costa - Doutorado 2010
- Eugenia Maria T. A. Campos - Mestrado 2017
- Eugênia Maria Teixeira de Araújo Campos – Doutorado 2019.2
- Gleison Vieira Duarte – Doutorado 2012
- Gleison Vieira Duarte – Mestrado 2009
- Huliana Mourão Carvalho - Mestrado 2017
- João Marcos da S. Carvalho - Mestrado 2017
- João Marcos da Silva Carvalho - DOUTORADO 2019.1
- José Abraão C. Neto – Mestrado 2013
- José Abraão Carneiro Neto – Doutorado 2014.2
- Keith Fróes Orrico - Mestrado 2017
- Kelly Morais Lima Nassri - Mestrado 2022.1
- Lívia Maria Alves de Oliveira - DOUTORADO 2019.1
- Maria de Lourdes Santana Bastos – Doutorado 2009
- Matheus Tannus dos Santos – Mestrado 2010
- Murilo Pedreira Neves Júnior – Doutorado 2009
- Rosana Cristina Pereira de Andrade – Doutorado 2013
- Rosana Cristina Pereira de Andrade – Mestrado 2010
- Sheila Nunes Ferraz L. de Matos - DOUTORADO 2019.1
- Sheila Nunes Ferraz Liberato de Matos – Mestrado 2018
- Tatiane Souza Soares de Oliveira - DOUTORADO 2019.1
- Tatiane Souza Soares de Oliveira - Mestrado 2016
- Tiago de Morais Alves da Cunha - Doutorado 2009
- Glyburide, a NLRP3 Inhibitor, Decreases Inflammatory Response and Is a Candidate to Reduce Pathology in Leishmania braziliensis Infection.
- Inhibition of Gamma-secretase activity without interfering in Notch signaling decreases inflammatory response in patients with cutaneous leishmaniasis.
- A double edged sword: Schistosoma mansoni Sm29 regulates both Th1 and Th2 responses in inflammatory mucosal diseases - 2016
- A Double-blind, Randomized Trial to Evaluate Miltefosine and Topical Granulocyte Macrophage Colony-stimulating Factor in the Treatment of Cutaneous Leishmaniasis Caused by Leishmania braziliensis in Brazil
- A Genome-wide Association Study Identifies SERPINB10, CRLF3, STX7 , LAMP3, IFNG-AS1 , and KRT80 As Risk Loci Contributing to Cutaneous Leishmaniasis in Brazil.
- A pilot and open trial to evaluate topical Bacterial Cellulose bio-curatives in the treatment of cutaneous leishmaniasis caused by L. braziliensis.
- Age Modifies the Immunologic Response and Clinical Presentation of American Tegumentary Leishmaniasis - 2015
- Analysis of expression of FLI1 and MMP1 in American cutaneous leishmaniasis caused by Leishmania braziliensis infection.
- Anti-Leishmania IgG is a marker of disseminated leishmaniasis caused by Leishmania braziliensis.
- Assessment of Immune and Clinical Response in Patients with Mucosal Leishmaniasis Treated with Pentavalent Antimony and Pentoxifylline.
- Association of miltefosine with granulocyte and macrophage colony-stimulating factor (GM-CSF) in the treatment of cutaneous leishmaniasis in the Amazon region: A randomized and controlled trial.
- Association of Sicca Syndrome with Proviral Load and Proinflammatory Cytokines in HTLV-1 Infection - 2016
- Atypical Manifestations of Cutaneous Leishmaniasis in a Region Endemic for Leishmania braziliensis: Clinical, Immunological and Parasitological Aspects - 2016
- Bladder dysfunction in human T cell lymphotropic virus infection: A prospective cohort study.
- Blockade of TLR2 and TLR4 Attenuates Inflammatory Response and Parasite Load in Cutaneous Leishmaniasis.
- Blood cytokines in atopic and non-atopic eosinophilic moderate to severe asthmatics.
- CD8+ T cell cytotoxicity mediates pathology in the skin by inflammasome activation and IL-1β production.
- Characterization of memory T cells in individuals resistant to Schistosoma mansoni infection.
- Characterization of Neutrophil Function in Human Cutaneous Leishmaniasis Caused by Leishmania braziliensis - 2016
- Characterization of the Histopathologic Features in Patients in the Early and Late Phases of Cutaneous Leishmaniasis.
- Clinical and histopathologic features of canine tegumentary leishmaniasis and the molecular characterization of Leishmania braziliensis in dogs.
- Clinical Profile and Diagnosis of Recurrent Cutaneous Leishmaniasis.
- Cutaneous Leishmaniasis Induces a Transmissible Dysbiotic Skin Microbiota that Promotes Skin Inflammation.
- Cutaneous Manifestations of Human and Murine Leishmaniasis.
- Detection of IgG Anti-Leishmania Antigen by Flow Cytometry as a Diagnostic Test for Cutaneous Leishmaniasis - 2016
- Diabetes Modifies the Clinic Presentation of Cutaneous Leishmaniasis.
- Diffusion tensor imaging metrics in diagnosis of HTLV-1-associated myelopathy.
- Dogs Harbor Leishmania braziliensis and Participate in the Transmission Cycle of Human Tegumentary Leishmaniasis.
- Effects of Physiotherapy in the Treatment of Neurogenic Bladder in Patients Infected With Human T-Lymphotropic Virus 1 - 2016
- Efficacy of intralesional meglumine antimoniate in the treatment of canine tegumentary leishmaniasis: A Randomized controlled trial.
- Evaluation of the Ability of Miltefosine Associated with Topical GM-CSF in Modulating the Immune Response of Patients with Cutaneous Leishmaniasis.
- Evolution of erectile dysfunction in individuals infected with human T-lymphotropic virus 1: a prospective cohort study.
- Fluconazole in the Treatment of Cutaneous Leishmaniasis Caused by Leishmania braziliensis : A Randomized Controlled Trial.
- Glyburide, a NLRP3 inhibitor, decreases inflammatory response and is a candidate to reduce pathology in Leishmania braziliensis infection.
- Harmonized clinical trial methodologies for localized cutaneous leishmaniasis and potential for extensive network with capacities for clinical evaluation.
- HCV/HTLV coinfection: Does HTLV-1 interfere in the natural history of HCV-related diseases? - 2016
- High Anti-Leishmania IgG Antibody Levels Are Associated With Severity of Mucosal Leishmaniasis.
- Human CD8+ T Cells Release Extracellular Traps Co-Localized With Cytotoxic Vesicles That Are Associated With Lesion Progression and Severity in Human Leishmaniasis.
- IL-22 Protects against Tissue Damage during Cutaneous Leishmaniasis - 2015
- Immune response to LinB13, a Lutzomyia intermedia salivary protein correlates with disease severity in tegumentary leishmaniasis.
- Immunological markers of protection in Leishmania (Viannia) braziliensis infection: A five years cohort study - 2016
- Impaired immunoregulatory network of the cd4 t lymphocytes in refractory asthma.
- Impaired Th1 Response Is Associated With Therapeutic Failure in Patients With Cutaneous Leishmaniasis Caused by Leishmania braziliensis.
- Impairment of the humoral and CD4+ T cell responses in HTLV-1-infected individuals immunized with tetanus toxoid - 2016
- In Situ Cellular Response Underlying Successful Treatment of Mucosal Leishmaniasis with a Combination of Pentavalent Antimonial and Pentoxifylline.
- In Vitro Immunomodulatory Activity of a Transition-State Analog Inhibitor of Human Purine Nucleoside Phosphorylase in Cutaneous Leishmaniasis
- Inflammasome Activation by CD8+ T Cells from Patients with Cutaneous Leishmaniasis Caused by Leishmania braziliensis in the Immunopathogenesis of the Disease.
- Inflammatory and immunological profiles in patients with COPD: relationship with FEV1 reversibility - 2016
- Influence of Obesity on Clinical Manifestations and Response to Therapy in Cutaneous Leishmaniasis Caused by Leishmania braziliensis.
- Insulin-like growth factor-I serum levels and their biological effects on Leishmania isolates from different clinical forms of American tegumentary leishmaniasis - 2016
- Interleukin 10-Dominant Immune Response and Increased Risk of Cutaneous Leishmaniasis After Natural Exposure to Lutzomyia intermedia Sand Flies - 2015
- Investigation of the pathways related to intrinsic miltefosine tolerance in Leishmania (Viannia) braziliensis clinical isolates reveals differences in drug uptake.
- Leishmania braziliensis causing human disease in Northeast Brazil presents loci with genotypes in long-term equilibrium.
- Leishmania braziliensis Infection Enhances Toll-Like Receptors 2 and 4 Expression and Triggers TNF-α and IL-10 Production in Human Cutaneous Leishmaniasis.
- Leishmania braziliensis Isolated from Disseminated leishmaniasis Patients Down Modulate Neutrophil Function.
- Meta-transcriptome Profiling of the Human-Leishmania braziliensis Cutaneous Lesion - 2016
- MicroRNAs regulating macrophages infected with Leishmania L. (V.) Braziliensis isolated from different clinical forms of American tegumentary leishmaniasis.
- Mucosal leishmaniasis: A Retrospective Study of 327 Cases from an Endemic Area of Leishmania (Viannia) braziliensis.
- Mucosal leishmaniasis: urgent need for more research.
- Multiomic profiling of cutaneous leishmaniasis infections reveals microbiota-driven mechanisms underlying disease severity.
- Neurologic, clinical, and immunologic features in a cohort of HTLV-1 carriers with high proviral loads.
- Neurological manifestations in HTLV-1 infected individuals without HAM/TSP: a longitudinal cohort study - 2015
- Neurological Manifestations in Human T-Cell Lymphotropic Virus Type 1 (HTLV-1)-Infected Individuals Without HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis: A Longitudinal Cohort Study - 2015
- NKG2D promotes CD8 T cell-mediated cytotoxicity and is associated with treatment failure in human cutaneous leishmaniasis.
- Onabotulinumtoxin type A improves lower urinary tract symptoms and quality of life in patients with human T cell lymphotropic virus type 1 associated overactive bladder.
- Oral Pentoxifylline Associated with Pentavalent Antimony: A Randomized Trial for Cutaneous Leishmaniasis.
- Osteopontin, CCL5 and CXCL9 are independently associated with psoriasis, regardless of the presence of obesity - 2015
- Phenotypic and functional characteristics of HLA-DR+ neutrophils in Brazilians with cutaneous leishmaniasis - 2016
- Phenotypic Characterization of CD4+ T Lymphocytes in Periportal Fibrosis Secondary to Schistosomiasis.
- Phonotherapeutic Intervention in Patients With Mucosal Leishmaniasis Sequelae.
- Pioglitazone, a Peroxisome Proliferator-Activated Receptor-γ Agonist, Downregulates the Inflammatory Response in Cutaneous Leishmaniasis Patients Without Interfering in Leishmania braziliensis Killing by Monocytes.
- Polymorphism in the interleukin-10 gene is associated with overactive bladder phenotype associated with HTLV-1 infection.
- Profile of T and B lymphocytes in individuals resistant to Schistosoma mansoni infection.
- Prostaglandin E2 contributes to L. braziliensis survival and therapeutic failure in cutaneous leishmaniasis.
- Protection and Pathology in Leishmania braziliensis Infection.
- Radiographic aspects in individuals infected by human T-lymphotropic virus type 1 (HTLV-1) with joint pain.
- Regulatory T cells control Staphylococcus aureus and disease severity of cutaneous leishmaniasis.
- Schistosoma mansoni antigens alter activation markers and cytokine profile in lymphocytes of patients with asthma - 2016
- Schistosoma mansoni antigens alter activation markers and cytokine profile in lymphocytes of patients with asthma.
- Schistosoma mansoni antigens alter activation markers and cytokine profile in lymphocytes of patients with asthma.
- Schistosoma mansoni rSm29 Antigen Induces a Regulatory Phenotype on Dendritic Cells and Lymphocytes From Patients With Cutaneous Leishmaniasis.
- Selective whole-genome amplification reveals population genetics of Leishmania braziliensis directly from patient skin biopsies.
- Serodiagnosis and therapeutic monitoring of New-World tegumentary leishmaniasis using synthetic type-2 glycoinositolphospholipid-based neoglycoproteins.
- Susceptibility of dendritic cells from individuals with schistosomiasis to infection by Leishmania braziliensis.
- The gp63 Gene Cluster Is Highly Polymorphic in Natural Leishmania (Viannia) braziliensis Populations, but Functional Sites Are Conserved - 2016
- The Influence of Infection by Different Leishmania (Viannia) braziliensis Isolates on the Pathogenesis of Disseminated Leishmaniasis.
- The Role of Nitric Oxide and Reactive Oxygen Species in the Killing of Leishmania braziliensis by Monocytes from Patients with Cutaneous Leishmaniasis - 2016
- The Role of NK Cells in the Control of Viral Infection in HTLV-1 Carriers.
- Tissue Damage in Human Cutaneous Leishmaniasis: Correlations Between Inflammatory Cells and Molecule Expression.
- TNF-induced metalloproteinase-9 production is associated with neurological manifestations in HTLV-1-infected individuals.
- Treatment of Disseminated Leishmaniasis With Liposomal Amphotericin B. - 2015
- Unbalanced production of LTB 4</sub> /PGE 2</sub> driven by diabetes increases susceptibility to cutaneous leishmaniasis.
- Variable gene expression and parasite load predict treatment outcome in cutaneous leishmaniasis.