Lucas Pedreira de Carvalho
Português, Brasil
Professor Adjunto de Imunologia da Universidade Federal da Bahia, possui graduação em Ciências Biológicas pela Universidade Católica do Salvador (2000), Mestrado em Patologia Humana pela Universidade Federal da Bahia (2002) e Doutorado em Patologia Humana pela Universidade Federal da Bahia (2005). Realizou o Pós-Doutorado em Imunologia na University of Pennsylvania. Tem experiência na área de Imunologia, com ênfase em Imunologia Aplicada, atuando principalmente nos seguintes temas: leishmaniose, candidíase vaginal e hanseníase.Pesquisador 2 do CNPq.
Titulação:
Doutor em Patologia Humana, UFBA
Vínculo:
Permanente
Email:
Telefone:
71. 32377353
Currículo Lattes:
Orientando:
- Camila Pimentel Santos - Mestrado 2022.1
- Camilla Sampaio Paixão - Doutorado 2017
- Fábio de Carvalho Peixoto - Doutorado 2022.1
- Fábio de Carvalho Peixoto - MESTRADO 2020.1
- Giovana Bergheme Franciscon – Doutorado 2013
- Giovana Bergheme Franciscon – Mestrado 2011
- Ivonete dos Santos Queiroz - Doutorado 2017
- Maurício Teixeira Nascimento - DOUTORADO 2019.1
- Maurício Teixeira Nascimento - Mestrado 2017
- Rubia Suely Costa – Doutorado 2013
- Rubia Suely Santana Costa – Mestrado 2011
- Taís Menezes Cerqueira Campos – Doutorado 2013
- Taís Menezes Cerqueira Campos – Mestrado 2012
Produção Científica:
- Anti-Leishmania IgG is a marker of disseminated leishmaniasis caused by Leishmania braziliensis.
- Brain-derived neurotrophic factor serum levels following ketamine and esketamine intervention for treatment-resistant depression: secondary analysis from a randomized trial.
- CD8+ T cell cytotoxicity mediates pathology in the skin by inflammasome activation and IL-1? production.
- CD8+ T cell cytotoxicity mediates pathology in the skin by inflammasome activation and IL-1β production.
- Cell adhesion proteins in the cerebrospinal fluid of neonates prenatally exposed to Zika virus: a case-control study.
- Characterization of the Histopathologic Features in Patients in the Early and Late Phases of Cutaneous Leishmaniasis.
- Characterization of the Histopathologic Features in Patients in the Early and Late Phases of Cutaneous Leishmaniasis.
- Clinical Presentation and Response to Therapy in Children with Cutaneous Leishmaniasis.
- Clinical Profile and Diagnosis of Recurrent Cutaneous Leishmaniasis.
- Comparative study of esketamine and racemic ketamine in treatment-resistant depression.
- Cross-reactivity using chimeric Trypanosoma cruzi antigens: diagnostic performance in settings co-endemic for Chagas disease and American cutaneous or visceral leishmaniasis.
- Cutaneous Leishmaniasis Induces a Transmissible Dysbiotic Skin Microbiota that Promotes Skin Inflammation.
- Cytotoxic activity in cutaneous leishmaniasis.
- Detection of IgG Anti-Leishmania Antigen by Flow Cytometry as a Diagnostic Test for Cutaneous Leishmaniasis - 2016
- Differential Host Pro-Inflammatory Response to Mycobacterial Cell Wall Lipids Regulated by the Mce1 Operon.
- Early Cutaneous Leishmaniasis Patients Infected with Leishmania braziliensis Express Increased Inflammatory Responses Following Antimony Therapy.
- Evaluation of monocyte subsets and markers of activation in leprosy reactions.
- Evaluation of the Ability of Miltefosine Associated with Topical GM-CSF in Modulating the Immune Response of Patients with Cutaneous Leishmaniasis.
- Glyburide, a NLRP3 inhibitor, decreases inflammatory response and is a candidate to reduce pathology in Leishmania braziliensis infection.
- Granzyme B Produced by Natural Killer Cells Enhances Inflammatory Response and Contributes to the Immunopathology of Cutaneous Leishmaniasis.
- High Anti-Leishmania IgG Antibody Levels Are Associated With Severity of Mucosal Leishmaniasis.
- IL-1β production by intermediate monocytes is associated with immunopathology in cutaneous leishmaniasis.
- IL-22 Protects against Tissue Damage during Cutaneous Leishmaniasis - 2015
- Immunological markers of protection in Leishmania (Viannia) braziliensis infection: A five years cohort study - 2016
- Impaired Th1 response is associated therapeutic failure in patients with cutaneous leishmaniasis caused by Leishmania braziliensis.
- Impairment of the humoral and CD4+ T cell responses in HTLV-1-infected individuals immunized with tetanus toxoid - 2016
- Inflammasome activation by CD8+ T cells from Patients with Cutaneous Leishmaniasis caused by Leishmania braziliensis in the immunopathogenesis of the disease..
- Influence of Obesity on Clinical Manifestations and Response to Therapy in Cutaneous Leishmaniasis Caused by.
- Inhibition of Gamma-secretase activity without interfering in Notch signaling decreases inflammatory response in patients with cutaneous leishmaniasis.
- Interleukin 10-Dominant Immune Response and Increased Risk of Cutaneous Leishmaniasis After Natural Exposure to Lutzomyia intermedia Sand Flies - 2015
- Leishmania braziliensis exosomes activate human macrophages to produce proinflammatory mediators.
- Localized skin inflammation during cutaneous leishmaniasis drives a chronic, systemic IFN-γ signature.
- Meta-transcriptome Profiling of the Human-Leishmania braziliensis Cutaneous Lesion - 2016
- Monocyte subpopulations study in patients with plaque psoriasis.
- Mononuclear Phagocyte Activation Is Associated With the Immunopathology of Psoriasis.
- NKG2D promotes CD8 T cell-mediated cytotoxicity and is associated with treatment failure in human cutaneous leishmaniasis.
- Peripheral lymphocyte subsets in chronic hepatitis C: Effects of 12 weeks of antiviral treatment with interferon-alpha plus ribavirin - 2016
- Pioglitazone, a Peroxisome Proliferator-Activated Receptor-γ Agonist, Downregulates the Inflammatory Response in Cutaneous Leishmaniasis Patients Without Interfering in Leishmania braziliensis Killing by Monocytes.
- Potential Role for Mononuclear Phagocytes in Cutaneous Ulcer Development in Human Immunodeficiency Virus-Leishmania braziliensis Coinfection - 2015
- Prostaglandin E2 contributes to L. braziliensis survival and therapeutic failure in cutaneous leishmaniasis.
- Regulatory T cells control and disease severity of cutaneous leishmaniasis
- Schistosoma mansoni rSm29 Antigen Induces a Regulatory Phenotype on Dendritic Cells and Lymphocytes From Patients With Cutaneous Leishmaniasis
- Selective whole-genome amplification reveals population genetics of Leishmania braziliensis directly from patient skin biopsies.
- The Elderly Respond to Antimony Therapy for Cutaneous Leishmaniasis Similarly to Young Patients but Have Severe Adverse Reactions.
- The Influence of Infection by Different Leishmania (Viannia) braziliensis Isolates on the Pathogenesis of Disseminated Leishmaniasis.
- The Leishmania antigen-specific pro-inflammatory response in cutaneous leishmaniasis is linked to disease progression but not to the therapeutic failure of pentavalent antimonials.
- The leprosy reaction is associated with salivary anti-Porphyromonas gingivalis IgA antibodies.
- The Role of NK Cells in the Control of Viral Infection in HTLV-1 Carriers.
- TNF-induced metalloproteinase-9 production is associated with neurological manifestations in HTLV-1-infected individuals.
- Unbalanced production of LTB 4</sub> /PGE 2</sub> driven by diabetes increases susceptibility to cutaneous leishmaniasis.
- Variable gene expression and parasite load predict treatment outcome in cutaneous leishmaniasis. Science Translational Medicine
